Lyme Disease and Pregnancy: State of the Science and Opportunities for Research. This Zoom Webinar will take place Thursday, April 29 from 5:00 – 6:30 pm EST. There is no charge to attend. In partnership with the National Institutes of Health to encourage new research in the field of tick-borne illness, this webinar will provide researchers the opportunity to learn about the application process and seek guidance from NIH program officers.
Search Results for: Lyme disease
Valneva and Pfizer announced that they have initiated a Phase 2 study for their Lyme disease vaccine candidate. This new study builds on previous studies, including new dose regimens as well as being the first clinical study to include children between the ages 5-17 years.
“Diagnosis, Treatment, and Prevention Practices for Lyme Disease by Clinicians, United States, 2013-2015” by Alyssa R. Beck, MPH, Grace E. Marx, MD, and Alison F. Hinckley, PhD, published in Public Health Report, February 4, 2021, presented a study the objective of which “was to better understand factors associated with clinical practices related to tick bites […]
The study, “A murine model of lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system,” was published in the journal PLOS Pathogens. Prior to this, studies using inbred laboratory mice to observe B. burgdorferi infection and host immune responses in the central nervous system (CNS) were lacking, creating a major barrier to understanding the neuropathologies associated with Lyme disease.
Tick-Borne Disease Working Group, Report to Congress 2020; David Hughes Walker, MD (Co-Chair); Leigh Ann Soltysiak, MS (Co-Chair); Charles Benjamine (Ben) Beard, PhD; Scott Palmer Commins, BS, MD, PhD; Angel M. Davey, PhD; Dennis M. Dixon, PhD; Sam T. Donta, MD; Adalberto Perez de Leon, DVM, MS, PhD; Kevin R. Macaluso, PhD; Patricia V. Smith, […]
This new summary article by employees of the CDC, presents the first county-level map of the distribution of Lyme disease spirochetes in host seeking Ixodes ticks between 2004-2019 in the contiguous United States. Data compiled for this summary was from literature searches; publicly available tick-borne pathogen surveillance databases (ArboNet Tick module); and internal CDC pathogen […]
Virulence of Borrelia involves multiple channels for transmission and establishment in multiple tissues, as well as evasion of the host immune responses. The bacteria undergo significant changes in gene expression and multiply and spread once transmitted to the host. These changes induce inflammatory responses that, in humans, result in clinical signs and symptoms of disease. In […]
The Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR) announced on November 30, 2020, new guidelines for prevention, diagnosis, and treatment of Lyme disease. Among the treatment recommendations, the guidelines recommend oral antibiotic therapy for most patients with Lyme disease. The recommended duration of therapy is […]
The Lyme Disease Association Inc. is providing you with information from the Centers for Disease Control & Prevention (CDC) on the U.S reported Lyme disease case numbers by county in each state for the years 2000-2018. 2000-2007 data reflect surveillance case definition at that time and reflect confirmed cases. 2008-present data reflect that surveillance case […]
With a new $3.5 million grant from the National Institutes of Health (NIH), Utpal Pal, PhD, professor in Veterinary Medicine at the University of Maryland (UMD) will be partnering with Matthias Schnell, director of the Jefferson Vaccine Center at Thomas Jefferson University to develop a novel “next-generation” Lyme disease vaccine. Pal, a tick immunobiologist, and […]