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Pfizer Cuts Enrollment Numbers in Lyme Vaccine Trial
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In a breaking Fierce Biotech news article, 08.22.2023, Pfizer announced that the number of people enrolled in the phase 3 clinical trial for the Lyme vaccine (VLA15) will be significantly […]
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In a breaking Fierce Biotech news article, 08.22.2023, Pfizer announced that the number of people enrolled in the phase 3 clinical trial for the Lyme vaccine (VLA15) will be significantly […]
Journal of Medical Entomology (Schulze, T.L., et al.) 08.04.2023 published an open access article, “Community-based integrated tick management programs: cost and feasibility scenarios.” In this article, researchers explore the cost […]
Open Forum Infectious Diseases (Ordaya E., et al.) 5.29.23 published “‘Let the Cat Out of the Heart’: Clinical Characteristics of Patients Presenting With Blood Culture-Negative Endocarditis Due to Bartonella Species.” The study was performed in an effort to define the clinical features of patients with Blood Culture-Negative Endocarditis (BCNE) due to Bartonella spp at Mayo Clinic in Rochester, Minnesota.
Infectious Disease Reports (Cosiquien, R.J.S., et al.) 06.26.2023 published “Anaplasma phagocytophilum Encephalitis: A Case Report and Literature Review of Neurologic Manifestations of Anaplasmosis.” In this case report, authors describe the […]
PNAS Nexus (Combs, M.A., et al) 08.2023, published “Host adaptation drives genetic diversity in a vector-borne disease system.” In this study investigators looked at the extent of intraspecific variation in Borrelia […]
Science Direct (Stevensen, B.) 08.2023, published “The Lyme disease spirochete, Borrelia burgdorferi, as a model vector-borne pathogen: insights on regulation of gene and protein expression.” In order to complete its […]
Journal of Medical Entomology (Eleftheriou, A., et al.) 08.2023, published “An established population of Asian longhorned ticks (Acari: Ixodidae) in Ohio, USA.” The Asian longhorned tick, Haemaphysalis longicornis Neumann, continues […]
The Clinical Infectious Diseases Journal (Mendoza M. A., et al.) 08.04.2023, published “Powassan virus encephalitis: a tertiary center experience.” In this study, the researchers collected and analyzed clinical and epidemiological data from patients who had been diagnosed with neuroinvasive POWV infection from a study conducted at the Mayo Clinic from 2013 to 2022.
Powassan virus (POWV) is a type of flavivirus that is transmitted by Ixodes spp ticks. This virus has been recognized as an emerging pathogen that can cause neuroinvasive diseases, which affect the nervous system, and can lead to serious outcomes. The study identified sixteen patients who had been infected with neuroinvasive POWV. Within 90 days of diagnosis, three cases (18.8%) resulted in the patients’ deaths. Among the survivors, eight patients (72.7%) experienced residual neurological deficits, indicating lasting effects on their nervous systems.
The Molecular Therapy Journal (Pine M., et al.) 08.01.2023, published “Development of an mRNA-lipid nanoparticle vaccine against Lyme disease.” In this study, scientists propose using a new method called “mRNA-LNP” to create a Lyme disease vaccine, similar to the successful COVID-19 vaccines. The vaccine would target a specific protein in the bacteria Borrelia burgdorferi that causes Lyme disease, called OspA. This protein is found on the surface of B. burgdorferi and is essential for its survival in ticks. By targeting this bacterium, the vaccine aims to prevent the bacteria from infecting humans when bitten by ticks.
In 1998, there was an alum-adjuvanted recombinant OspA protein vaccine release called LYMErix™, that showed to decrease Lyme disease by 75% within a year, but the vaccine was removed from the market in 2002, just four years after its release. Since then, there has been no FDA-approved vaccine for Lyme disease, while cases continue to rise.
Medical Xpress released an article “A vaccine that reduces ability of ticks to transmit Lyme disease bacteria” on 8.2.2023, written by Bob Yirka and Medical Xpress. The article focuses on a team of medical students and colleagues who have developed a type of vaccine to try and reduce the ability of ticks transmitting the bacteria that cause Lyme disease. This vaccine would be given to a host animal to prevent ticks from spreading the disease.
LDA Doctor Referral System © Terms & Conditions and Guidelines
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About LDA DOCTOR REFERRAL SYSTEM ©
Welcome to the Lyme Disease Association’s LDA Doctor Referral System ©. LDA made updates and enhancements to its prior system and has launched a new site to provide patients with information about doctors, other practitioners, testing labs, and pharmacies that are knowledgeable about chronic Lyme disease and often about many other tick-borne diseases (TBD). Many of the doctors listed are often referred to as Lyme Literate Physicians/Doctors (LLMD). Tens of thousands of patients have successfully used the prior LDA system to locate Lyme and TBD resources.
Terms & Conditions and Guidelines
Because there is a negative political climate surrounding Lyme disease, many LLMDs do not want their names posted outright on the internet. LDA has tried to balance the doctors’ wishes with patients’ need to find a doctor. This new system is a result of that compromise and therefore:
Because of the limited number of physicians treating chronic Lyme disease nationwide, some states, and in some instances, entire regions, may not have any treating physicians who follow flexible treating approaches such as those in the International Lyme & Associated Diseases Society (ILADS) Guidelines, Evidence Assessments and Guideline Recommendations in Lyme Disease: The Clinical Management of Known Tick Bites, Erythema Migrans Rashes and Persistent Disease. In the event that the LDA Doctor Referral System © contains no Lyme or TBD resource listings in a given area, the closest possible option(s) will populate based on the location entered and specaialty/ies selected. The LDA appreciates any changes in provider information that you may find and make us aware of so we can investigate.
Some providers may not specifically treat Lyme and TBD but see patients who have symptoms associated with Lyme and TBD to address those specific symptoms. Contact the provider to confirm.
It is your responsibility to contact the provider’s office to confirm the current address, directions, nature of services provided, and all other provider information before you make an appointment.
DISCLAIMER: The Lyme Disease Association, Inc. provides referrals to health care providers who treat Lyme disease, and often other TBD, as a courtesy to those seeking Lyme Literate Physicians (LLMD). However, some of the providers included do not specifically treat Lyme and TBD but see patients who have symptoms associated with Lyme and TBD to address those specific symptoms. We do not evaluate the professional competence or qualifications of health care providers on our referral list or the costs of services provided. Accordingly, the LDA neither warrants nor endorses the health care providers contained on this list nor the quality of care you will receive from those providers. We do not make recommendations, only referrals. LDA does not receive any monies from physicians to be included on this list nor does LDA provide any monies to physicians. Because of the limited number of physicians treating chronic Lyme disease nationwide, some states, and in some instances, entire regions, may not have any treating physicians who follow flexible treating approaches such as those in the International Lyme & Associated Diseases Society (ILADS) Guidelines: Evidence Assessments and Guideline Recommendations in Lyme Disease: The Clinical Management of Known Tick Bites, Erythema Migrans Rashes and Persistent Disease. In the event that the Doctor Referral System contains no Lyme or TBD resource listings in a given area, the closest possible option(s) will populate based on the zip code entered and category/ies selected. The LDA appreciates any changes in provider information that you may find and make us aware of.
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We cannot guarantee that the information provided will be timely and accurate or that physicians on the list are accepting new patients, or that they accept insurance. The selection of a physician should be made by you after careful consideration. There are two approaches in the treatment of Lyme disease. Our list contains physicians who generally follow more flexible treatment approaches than those advocated by the Infectious Diseases Society of America (IDSA). LDA is not responsible for incorrect information on the website. BEFORE DOCTOR VISIT: Please contact the physicians’ offices directly to confirm their current address, directions, and any other necessary information before scheduling an appointment. Do not rely only on the maps provided on this site. The maps on LDA’s Doctor Referral System are for informational purposes and provide an approximate locality of the listing based on the addresses we are provided with at the time of site updates. Practitioners often relocate and addresses can change. Notification of changes in listed information can be updated on our Dr. Referral Contact Form. Thank you, Lyme Disease Association, Inc. (LDA)
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