Parasitology Research has published research findings on the effectiveness of the Seresto® (imidacloprid 10% + flumethrin 4.5%) dog collar in preventing transmission of both Borrelia burgdorferi and Anaplasma phagocytophilum. Effectiveness of the prevention collar was tested on dogs in two studies using naturally infected ticks. Each study consisted of a non-treated control group as well as a group treated with the Seresto® collar. All dogs were serologically tested for the presence of pathogens prior to study implementation.
The treated groups of dogs were fitted with Seresto® collars two months prior to tick infestations. All dogs were exposed to ticks that were naturally infected with B. burgdorferi and A. phagocytophilum. In study 1, two of six non-treated dogs became infected with B. burgdorferi, and four of six tested positive for A. phagocytophilum after being exposed to naturally infected Ixodes ricinus ticks. In study two, 10 of 10 non-treated dogs became infected with B. burgdorferi and A. phagocytophilum after being exposed to naturally infected Ixodes scapularis ticks. None of the treated dogs in either study tested positive for B. burgdorferi or A. phagocytophilum. Transmission of both pathogens was successfully blocked for up to 7 months on dogs wearing Seresto® collars.
Investigators reported that no serious treatment-related events were found with use of the Seresto® collar in the treated groups of dogs. Only mild signs of hair loss and skin irritation were observed, primarily in the group dogs treated for 7 months. The use of the acaricide collar showed 100% efficacy for killing ticks at 48 h for both tick species at time periods of 1, 2 and 7 months after the placement of the collar.
Authors conclude that due to its long-term efficacy, the Seresto® collar may be a valuable tool in the prevention of tick pathogen transmission to dogs.
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