Myocarditis Case Reports: Post COVID Vaccination

The Journal of the American Medical Association (Oster, M.E. et al) published “Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021” on January 25, 2022. The authors published a descriptive study that analyzes reports of myocarditis from 192,405,448 US individuals (>12 years of age) to the Vaccine Adverse Event Reporting System (VAERS) after receiving COVID-19 vaccines. Cases of adverse events were reported for both BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) vaccinations between December 2020 – August 2021. 

Results of the study show that 1626 of 1991 reports of myocarditis to VAERS met the case definition of myocarditis.  The median age for those with myocarditis was 21 years with the median time to onset of symptoms being two days post vaccination. 82% of the cases (where sex was reported) were male. The highest rates across the study were observed in individuals after receiving a second dose of vaccination, with increased risk observed in both adolescent and young males. 

Authors suggest that the risks/benefits of COVID vaccination should be considered. 

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