Lewy Body Dementia Associated with Borrelia in the Brain

From: Alan B. MacDonald’s, “Microbial DNA globular liquid crystal-like deposits inside Lewy bodies in four Lewy dementia patients,” Med Clin Res, 2022.

Medical and Clinical Research published Alan B. MacDonald’s review article, “Microbial DNA globular liquid crystal-like deposits inside Lewy bodies in four Lewy dementia patients,” on August 10, 2022. Through review, MacDonald found evidence of both diffuse cortical Lewy body dementia and active neuroborreliosis in four autopsied brains.

The brains autopsied in this study were donated to the Dr. Paul H Duray MD Research Foundation to examine specifically for the possibility of undiagnosed Borrelia infections. The brains that were donated came from patients that had been exhibiting clinical signs and symptoms suggestive of Lewy body dementia, including visual hallucinations and progressive dementia.

Borrelia specific DNA probes and borrelia specific immunohistochemistry were used to confirm active Borrelia infection in these brains and immunohistochemistry results confirmed the pathological diagnosis of Lewy body dementia. MacDonald provides the first report of an association between Lewy body dementia and neuroborreliosis. 

NOTE: Copyright: ©2022: Alan B MacDonald. This is an open-access article
distributed under the terms of the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any
medium, provided the original author and source are credited.

 


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