Lyme Recovery in Mice Impacted by Impaired Sleep

Lyme Recovery in Mice Impacted by Impaired SleepScience Direct (Jackson, C.D., et al.) 01.13.2024, published “Sleep fragmentation disrupts Lyme arthritis resolution in mice.” In this study, researchers used a mouse model to investigate the effect of disrupted sleep on the progression and resolution of joint inflammation in Lyme arthritis.

Findings demonstrated a significant delay in resolution of Lyme arthritis (measured by swelling of joints, severity scores of arthritis, and decreased bacterial clearance from joints) when initiation of sleep fragmentation occurred at the peak of arthritis inflammation. Poor sleep may interrupt clearance of Lyme spirochetes and may increase both duration and severity of disease.

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