The new findings in this just published article were presented at the LDA/Columbia conference on Oct. 16, 2016 by Dr. Ying Zhang, Johns Hopkins.
The research demonstrates the results of specific drug treatment for B. burgdorferi persisters, including single drug pulse dosing, combination drug pulse dosing; and which approaches are more effective at killing resistant biofilm-like microcolonies of persisters.
Ceftriaxone Pulse Dosing Fails to Eradicate Biofilm-like Microcolony B. burgdorferi Persisters Which Are Sterilized by Daptomycin/Doxycycline/Cefuroxime Drug Combination without Pulse Dosing
Jie Feng1, Shuo Zhang1, Wanliang Shi1 and Ying Zhang1*
1Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University,