CoQ10 Supplement as Support to Lyme Treatment?

In this article, authors review the potential role of coenzyme Q10 (CoQ10)  as a supplementation to moderate the pathogenic mechanisms underlying Lyme disease symptoms; specifically mitochondrial dysfunction, oxidative stress and inflammation. CoQ10 is a “vitamin-like” substance synthesized within most tissues in the human body that has shown effective at mediating these processes.

Lyme symptoms such as fatigue, neurologic issues, cardiac issues, and joint inflammation may benefit from supplementation with CoQ10 as it can reduce damage to the tissues resulting from excessive inflammatory responses in the body. This substance is important to many functions in cellular metabolism as well as protecting from free-radical oxidative stress. CoQ10 has also been shown to mediate the expression of a large number of genes directly. It’s impacts to gene expression involved in the process of inflammation alone can have direct effect on many Lyme symptoms.

Authors state that more than 50 randomized controlled clinical studies relating to CoQ10 and inflammation, in a variety of disorders, are currently listed on Medline. Most of the studies looking at CoQ10 supplementation have resulted in significant reductions in inflammatory markers. However, no studies have yet assessed the potential CoQ10 benefit Lyme disease patients following supplementation.

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