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Paralytic Late Tick-Borne Disease: Borrelia, Babesia, Anaplasma, Bartonella

 

Photo by billow926 on UnsplashThe Antibiotic Journal (Trouillas P. & Franck M.) 06.07.2023, published “Complete Remission in Paralytic Late Tick-Borne Neurological Disease Comprising Mixed Involvement of Borrelia, Babesia, Anaplasma, and Bartonella: Use of Long-Term Treatments with Antibiotics and Antiparasitics in a Series of 10 Cases.”

“This study aimed to demonstrate that severe neurological motor deficits in the context of late tick-borne disease with mixed microorganism involvement are eligible for long-term combined antibiotic/antiparasitic treatments.” Patients that met the inclusion criteria were with treated multiple cycles of different antibiotics and antiparasitics. Before treatments, a group of 10 patients had severe motor deficits including needing wheelchairs and using walking sticks. After treatment, 7 out of the 10 patients showed complete remission. The other 3 patients showed initial remission but later suffered antibiotic/antiparasitic-resistant motor reoccurrences. Another group of 9 patients showed 7 patients in total remission.

Researchers indicated limitations such as it is a case series, not a trial, and only suggests scientific conclusions; not high number of patients; ruled-out disease criteria might be discussed; testing issues and immunoblot interpretations might also be discussed, since analysis criteria are different in Europe, US, and China.


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Read the article on the Antibiotic Journal website.