The early stage of cutaneous Lyme is frequently distinguished by the erythema-migrans patch, which manifests within a month after being bitten by an infected tick. Numerous erythema migrans variants have now been documented, prompting a case study by Hayden Doughty, BS, et al. that was recently published in Journal of the American Academy of Dermatology. The case series examines the occurrence of bullous erythema migrans, a rare and blistering form of erythema migrans, in three patient cases.
This Research Articles section includes articles on cutting edge research or on research which has been conducted on already existing research to either substantiate it or question its findings. The Peer Review Articles submenu sections includes only research in peer-reviewed journals–in which a panel of experts in the same field as the authors reviews the articles prior to publication to ensure scientific quality. The Professional/Govt Articles submenu contains articles by professionals or government without those articles going through the peer-review process.
In a recent publication of Emerging infectious Diseases, researchers analyzed reported Lyme disease cases in endemic states to assess the total patient and societal cost. The study by Hook SA, Jeon S, Niesobecki SA, et al (Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014–2016) analyzed reported Lyme disease cases in […]
In a recent publication of the International Journal of Environmental Research and Public Health, researchers utilized an online questionnaire to determine which factors were associated with Lyme disease. They compared responses between both patients with and without Lyme disease that were recruited through Social media outlets, Lyme disease support groups in NY, NJ & PA, […]
Babesia Duncani Study to Better Understand Susceptibility & Virulence of Intraerythrocytic Parasites
Anasuya C. Pal, et al., published a study using Babesia duncani as a model to further assess intraerythrocytic parasites in The Journal of Infectious Diseases. The researchers investigated the development, virulence, and susceptibility of the organism in vitro and in vivo to gain a better understanding of its biology and pathogenesis
Positive Phase 2 clinical trial results for the Lyme disease vaccine candidate (VLA15) in the pediatric population have just been announced by Pfizer and Valneva. VLA15 is currently the only Lyme disease vaccine candidate in clinical development, and is the first clinical study to enroll children aged 5 to 17 years old. This phase 2 […]
The University of Utah Health website has reported news from the university’s Division of Microbiology and Immunology and their recent discovery of a new genetic pathway that might help to uncover why some patients develop more severe cases of Lyme disease arthritis.
In this mini review article, researchers examine the important and potential role of antibiotic tolerance/persistence in Borrelia spp. (Lyme disease bacteria) and Post treatment Lyme Disease Syndrome (PTLDS). Many hypotheses have been proposed and studies have been conducted to attempt to determine the potential causes of persistent Lyme disease or PTLDS. Studies have examined autoimmunity, […]
LDA Congratulates James Occi (Jim), who recently received his PhD at Rutgers University, the Center for Vector Biology (New Brunswick), and wishes him every success with his future endeavors. He studied tick-borne diseases in New Jersey tick populations under the direction of Dr. Dina Fonseca and co-authored the below four published research articles for his dissertation.
The Journal of Nervous and Mental Disease, May 2022, published Persistent Symptoms, Lyme Disease, and Prior Trauma, by Mustafiz et al. The study examined 60 individuals with persistent symptoms after Lyme disease. Trauma history, mental and physical symptoms, and functional status were measured with validated methods. One prior study concluded that traumatic events before Lyme […]
Science Direct has just published a case report of a child in Massachusetts that was diagnosed and treated in the ER with “isolated Lyme radiculoneuritis” (inflammation of the spinal nerve roots). The child’s symptoms included fever and allodynia (severe sensitivity or heightened pain response) of the upper back. Though isolated radiculoneuritis is considered to be […]