A study by Mikhail et al in Open Forum Infectious Diseases, Feb. 2021, from 2006 to 2017 showed 19,469 beneficiaries had babesiosis recorded, a substantial increase. The highest states by rates were Massachusetts (62), Rhode Island (61), Connecticut (51), New York (30), and New Jersey (19). States previously considered nonendemic saw increases: New Hampshire, Maine, […]
This Research Articles section includes articles on cutting edge research or on research which has been conducted on already existing research to either substantiate it or question its findings. The Peer Review Articles submenu sections includes only research in peer-reviewed journals–in which a panel of experts in the same field as the authors reviews the articles prior to publication to ensure scientific quality. The Professional/Govt Articles submenu contains articles by professionals or government without those articles going through the peer-review process.
The Tick-Borne Disease Working Group (TBDWG) was established by the 21st Century Cures Act to improve federal coordination of efforts related to tick-borne diseases. The TBDWG’s purpose is to review federal activities and research related to all tick-borne diseases and provide a summary of its findings and any recommendations regarding changes or improvements to such findings to the HHS Secretary and Congress every two years.
The Tick-Borne Disease Working Group 2020 Report to Congress is now available (Report). The Report was presented to the Secretary of Health & Human Services in December 2020 by the Working Group (WG). The Secretary sent the Report to the Energy & Commerce Committee in the House of Representatives and the Health, Education, Labor, and Pensions […]
The study, “A murine model of lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system,” was published in the journal PLOS Pathogens. Prior to this, studies using inbred laboratory mice to observe B. burgdorferi infection and host immune responses in the central nervous system (CNS) were lacking, creating a major barrier to understanding the neuropathologies associated with Lyme disease.
The Pike County (PA) Tick Borne Diseases Task Force has provided a 6 minute video slide show with results from the Pike County Tick Borne Diseases Base-Line Study, a county-wide assessment of the tick-borne diseases and infection rates of ticks funded in part by a 2018 grant awarded by the LDA. From Spring 2018 […]
The study “Borrelia burgdorferi Sensu Stricto DNA in Field-Collected Haemaphysalis longicornis Ticks, Pennsylvania, United States” was recently published in the Centers for Disease Control & Prevention (CDC) Emerging Infectious Diseases. Pennsylvania has the highest number of reported Lyme disease cases in the US.
This new summary article by employees of the CDC, presents the first county-level map of the distribution of Lyme disease spirochetes in host seeking Ixodes ticks between 2004-2019 in the contiguous United States. Data compiled for this summary was from literature searches; publicly available tick-borne pathogen surveillance databases (ArboNet Tick module); and internal CDC pathogen […]
Does Bartonella Contribute to the Occurrence of Cutaneous Lesions and Neuropsychiatric Symptoms in Patients?
Results of the study, “Bartonella Associated Cutaneous Lesions (BACL) in People with Neuropsychiatric Symptoms” was recently published in the journal, Pathogens, as part of the special issue, “The Evolving Biomedical Importance of Bartonella Species Infections.” The study’s authors describe Bartonella spp. test results for participants who reported neuropsychiatric symptoms, with a majority reporting the concurrent incidence of cutaneous lesions.
The CDC published, in the February edition of its “Emerging Infectious Diseases,” two new papers pertaining to Lyme disease case numbers. CDC indicates that the researchers found ~ 476,000 people are diagnosed with and treated for Lyme disease each year in the U.S. This is a 59% increase from their previous estimate of ~300,000. Also, CDC posted a new page to its website, Syndromic Surveillance of Emergency Department Visits for Tick Bites, showing tick bites by time, age/sex, and region.
Virulence of Borrelia involves multiple channels for transmission and establishment in multiple tissues, as well as evasion of the host immune responses. The bacteria undergo significant changes in gene expression and multiply and spread once transmitted to the host. These changes induce inflammatory responses that, in humans, result in clinical signs and symptoms of disease. In […]