New in vitro study on dapsone (diaminodiphenyl sulfone), and dapsone combination therapy (DDS CT) was just published by Dr. Richard Horowitz et al. and provides hope of effective treatment for patients with persistent Lyme disease. The study is suggestive that dapsone combination therapy may well characterize both a novel and successful option to treat Borrelia […]
Lyme disease is a bacterial disease which in the US is caused by the bacteria Borrelia burgdorferi or newly discovered Borrelia mayonii. The bacteria can attack all of the systems in the body and produce many different Lyme disease symptoms, which is why it has often been called the great imitator. Women with Lyme disease who are pregnant or are thinking of becoming pregnant need to receive appropriate care from a knowledgeable Lyme disease doctor. Information on Lyme and pregnancy can be found in this section. Guidelines which help doctors with Lyme treatment have been developed and some can be found here, as well as various photos and videos pertaining to Lyme disease bacteria.
West Virginia University researchers received a $1.9 million grant from the National Institute of Allergy and Infectious Diseases, an institution of the National Institute of Health (NIH), for a vaccine to prevent humans from contracting Lyme disease. Mariette Barbier, assistant professor in the School of Medicine’s Department of Microbiology, Immunology and Cell Biology, is leading […]
With a new $3.5 million grant from the National Institutes of Health (NIH), Utpal Pal, PhD, professor in Veterinary Medicine at the University of Maryland (UMD) will be partnering with Matthias Schnell, director of the Jefferson Vaccine Center at Thomas Jefferson University to develop a novel “next-generation” Lyme disease vaccine. Pal, a tick immunobiologist, and […]
Lyme Disease Symptoms & Signs Lyme disease symptoms can affect any system in the body and can mimic symptoms of many different diseases. Lyme Disease Symptoms Compiled by the LDA As listed in the LDA LymeR Primer Available for online ordering As listed in the LDA Spanish LymeR Primer Available for Downloading Click dropdown arrows […]
Clinical practice treatment guidelines are often used as reference by physicians for Lyme disease treatment and treatment of other tick-borne diseases. The LDA provides some links here for informational purposes only, as LDA does not make specific treatment recommendations. The only Lyme disease treatment guidelines that that were posted on the National Guidelines Clearinghouse (NGC), […]
Valneva announced that the vaccine candidate against Lyme disease, VLA15-201, showed positive initial results meeting its endpoints in the Phase 2 study. They stated in the July 22, 2020 press release that “compared to Phase 1, the higher doses used in this trial elicited higher antibody responses across all serotypes.” Of particular note was the […]
The picture in New Jersey of spotted fever group rickettsiosis (SFGR), which includes Rocky Mountain Spotted fever (RMSF), is complex. In this latest study from the Am. Journal of Tropical Medicine and Hygiene (James Occi, Rutgers University, et al, ), the researchers tested American dog ticks and lone star ticks in NJ to determine which […]
Elizabeth L. Maloney, MD, President of the Partnership for Tick-Borne Diseases Education and Family Medicine Physician in Wyoming, MN published a paper titled “Reducing the Burden of Lyme Disease” in Minnesota Family Physician. It includes discussion of tick bite management, early treatment, and shared decision-making.
Elizabeth Maloney, MD, explains current Lyme disease testing issues, including the ELISA and Western Blot, sensitivity and specificity of the testing, and the problems associated with the two-tier testing recommended by the CDC. It begins with the general characteristics of diagnostic testing The Summary states: “Serologic testing for Lyme is inaccurate. While the inadequate sensitivity […]