The study “Borrelia burgdorferi Sensu Stricto DNA in Field-Collected Haemaphysalis longicornis Ticks, Pennsylvania, United States” was recently published in the Centers for Disease Control & Prevention (CDC) Emerging Infectious Diseases. Pennsylvania has the highest number of reported Lyme disease cases in the US.
About Milena Pastore
Posts by Milena Pastore:
New IDSA Guidelines/Failure to Commandeer Patient Chapter/#GivingTues/New Test for Lyme/CO Ticks/Updated COVID Protocol/Canine-Human Lyme Data/Next WG Meeting/LDA Thanks 51 Groups/DoD: Funds Lyme Vaccine
The Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR) announced on November 30, 2020, new guidelines for prevention, diagnosis, and treatment of Lyme disease. Among the treatment recommendations, the guidelines recommend oral antibiotic therapy for most patients with Lyme disease.
A new study published in Infectious Disease Modelling examines the relationships between incidence, prevalence, and total infection burden for Lyme borreliosis (LB) using sentinel canine and human seroprevalence data.
The researchers developed two models to estimate LB cases. One analyzed seroprevalence of Borrelia infections in human samples, applying corrections for false negative and false positive results from published test sensitivity and specificity measures.
Working Group Fight Continues/Horowitz Treatment Study/PA Tick Infection Rates/MyLymeData/COVID-19 & TBD/LymeX
Pat Smith in WG meeting on geographic boundaries preventing Lyme diagnosis: “I lived in the world of patients for 36 years, and I can tell you that they are not getting treated in those states because the government and other entities are telling them there is no disease. They are consistently not being diagnosed and treated, and you think this because there is a positive test they will get treated? No way. That doesn’t happen …
A new study lead by researchers from the University of California Los Angeles (UCLA) analyzed data from the MyLymeData patient registry. The Registry, with over 13,000 enrolled patients, is a project of the non-profit LymeDisease.org.
The researchers used machine learning techniques and analyzed more than 2,000 patients with chronic Lyme disease (CLD) from the database to identify key features associated with improved patient response. They found that the extended use of antibiotics was an important element of improved health.
Richard Horwitz, MD, et al., have published a new case study and retrospective chart review of 40 patients on double dose dapsone combination therapy (DDD CT) in the journal Antibiotics.
The study found that of the 40 patients analyzed, an 8-week course of dapsone combined with doxycycline and rifampin effectively improved symptoms in 98% of patients, as well as led to long-term remission in 45% of the total patients studied, even though most of the individuals were ill for a decade or longer.
The U.S. Department of Health and Human Services (HHS) and the Steven & Alexandra Cohen Foundation announced a
new $25 million-dollar, public-private partnership – the LymeX Innovation Accelerator (LymeX).
The HHS website states, “Our LymeX mission is to strategically advance Lyme and tickborne disease solutions in direct collaboration with Lyme patients, patient advocates, and diverse stakeholders across academia, nonprofits, industry, and government.”
A study published in the journal Diagnostic Microbiology and Infectious Disease addresses the observed negative effects of the COVID-19 pandemic on the timely diagnosis of tick-borne infections (TBD) in three adult patients.
Promising Dapsone Research/WG Meeting: Access to Care Under Attack/CDC Announces Nat’l Framework/Researchers ID Bat Tick in NJ/NIH Grants $1.9M for Lyme Vaccine/Lyme & Pregnancy Study/Oct 27 Next TBDWG Mtg
Dr. Richard Horowitz et al. just published a new in vitro study on dapsone (diaminodiphenyl sulfone) and dapsone combination therapy (DDS CT). The study is suggestive that dapsone combination therapy may well characterize both a novel and successful option to treat Borrelia burgdorferi “persister” cells, which are the biofilm form of the bacteria.
First announced at the HHS Tick-Borne Disease Working Group’s (TBDWG) September 22 meeting, the Centers for Disease Control (CDC), in a Capitol Hill Announcement, presented plans to join with five federal departments and the Environmental Protection Agency in developing the National Public Health Framework for the Prevention and Control of Vector-Borne Diseases in Humans (Framework). […]